Fiore has been coding computers, and soon moved to early network hosting a BBS in his room in the late 80s, getting a Computer Science degree, founding two IT startups, managing EU IST research projects, building web and mobile apps and consulting to companies. In his late thirties he realized that software alone cannot make a real impact in the world, and he started to get involved in the local Fab Lab movement first, then joining the Fab Academy and opening a public access Fab Lab in his town, Cascina, Italy. He is currently running a network of digital fabrication labs all over Tuscany, connecting projects and infrastructure for a future of distributed manufacturing and education, and is lead manager of infrastructure for different educational programs in the Fab Lab network such as Fab Academy, Fabricademy and Bio Academy.

In 2017 he started Fabctory – recipes for innovation, a spin off services company of Fab Lab Toscana, with the goal of training the network and implementing local production of global design around the world, using the micro-factory model.